国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2009, Vol. 28 ›› Issue (6): 387-389.

• 综述 • 上一篇    下一篇

体外培养中代谢分析评估胚胎发育潜能

赵红岩;孙莹璞   

  1. 450052 郑州大学第一附属医院生殖中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-11-15 发布日期:2009-11-15

The Application of Metabolism Analysis in In-vitro Culture Preimplantation Embryos Assessment

ZHAO Hong-yan;SUN Ying-pu   

  1. Reproductive Medical Center of the First Affiliated Hospital of Zhengzhou University， Zhengzhou 450052， China
  • Received:1900-01-01 Revised:1900-01-01 Published:2009-11-15 Online:2009-11-15

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摘要： 单胚胎移植（SET）是降低多胎妊娠率的一种有效方法，选择高质量的胚胎是提高单胚胎移植成功率的关键。目前，大多数生殖中心采用的胚胎形态学评分及卵裂率仍然是主要的评估方法，但在评估胚胎活力和预测继续妊娠方面具有一定的局限性。近期研究表明，胚胎代谢分析结合当前的评估方法，可能会更有效地选择优质胚胎，提高妊娠率同时降低多胎妊娠率。

关键词: 单胚胎移植, 胚胎发育潜能, 体外培养, 代谢评价

Abstract: Single embryo transfer（SET） is a useful method to reduce multiple pregnancies （MP） rate， the optimal embryo selection is the key factor to maintain success rates with SET. Presently，morphology and cleavage rate used in many centers remain the mainstay of embryo assessment， but they have a limited predictive value for assessing viability and ongoing pregnancy. Recent studys indicate that the metabolism analysis combinded with the current methods of embryo assessment would be more effective to select high-quailty embryos， increase the rate of pregnancy as well as reduce multiple pregnancies （MP） rate.

Key words: Single embryo transfer, Embryonic development, Culture in vitro, Assessment