Abstract: Objective：To investigate the factors of the complete intrauterine device (IUD) perforation, and to evaluate the safety of IUD in clinical application. Methods：A total of 56 cases of the complete IUD perforation were included in this study. The clinical characters and the related factors were analyzed. Results：In all of the 56 cases, 20 cases (35.71%) were found that the IUD insertion time was on the lactation period, and 24 cases (42.86%) used IUD for the first time. Abdominal pain was the main symptom in 25 cases (55.36%). IUD was translocated into the bladder in 10 cases(17.86%). Ectopic IUD was successfully removed by laparoscopy in 22 cases (39.29%). Conclusions：Many factors, such as the IUD model, using span and use for the first time, could be related to the complete IUD perforation. Women using IUDs for the first time should have the regular follow-up visit. Abdominal pain in those IUD users should be noticed during the routine follow-up visit.

Key words: Intrauterine device expulsion, Intrauterine devices, Perforation