Abstract: Androgen insensitivity syndrome (AIS), also known as testicular feminization syndrome, is an X-linked genetic disease. AIS is a common type of male pseudohermaphroditism. It can be divided into complete AIS and incomplete AIS. The main reason is that the mutations of androgen receptor gene lead to androgen resistance and non-response. The clinical data, diagnosis and treatment of two patients with CAIS in our hospital are reviewed in order to further improve the cognition, diagnosis and treatment of the disease.

Key words: Complete androgen insensitivity syndrome；, Androgen-insensitivity syndrome；, Gonadal dysgenesis, 46, XY；Magnetic resonance imaging；, Cryptorchidism；, Estrogen replacement therapy