Research Progress of Bioinformatics Technology in Reproductive System

doi:10.12280/gjszjk.20220361

Abstract

Abstract:

Bioinformatics is widely used in the studies of reproductive system at various technical levels, including genome, transcriptome, proteome and metabolome. Through systematic data collection and visual processing, the mechanisms of key molecules in the reproductive process have been gradually discovered and elucidated. The application of bioinformatics technology in reproductive system not only has effectively promoted the development and innovation of reproductive system research on the basis of ensuring preciseness and scientificity, such as analyses of the normal functions, abnormal and pathological phenomena of different reproduction organs at the different levels of genome, transcriptome, proteome and metabolome, but also has enhanced the progress of clinical diagnosis and treatment of the related diseases in reproductive system, such as the discoveries of new disease markers and drug targets for the diagnosis and treatment. In this review, we mainly introduced the latest bioinformatics technologies in the reproductive medicine in recent years. Meanwhile, we also summarized the current research progress in reproductive system using bioinformatics, which may provide some key guidance and ideas for future research.

Key words: Urogenital system, Computational biology, Genome, Transcriptome, Proteome, Metabolome

ZHOU Li-wei, ZHENG Shu-dong, HUANG Shuo, LU Ting, LIU Yue, DING Zhi-de. Research Progress of Bioinformatics Technology in Reproductive System[J]. Journal of International Reproductive Health/Family Planning, 2022, 41(6): 487-493.

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