Research Progress of Bisphenol A on Female Reproductive Function Injury and Drug Intervention

doi:10.12280/gjszjk.20220510

Abstract

Abstract:

Bisphenol A (BPA) as an organic compound widely existing in the environment can interfere with the normal metabolism of the body and participate in the occurrence and development of a variety of diseases. High dose BPA exposure has an acute toxic effect on the reproductive system. Long-term exposure to BPA has more significant damage to the reproductive system, and can even produce intergenerational effects, affecting the growth and development of offspring. BPA damages female reproductive function and reduces female fertility through a variety of mechanisms. Therefore, it is particularly important to develop related drugs to alleviate this adverse reaction. This paper reviews the effects of BPA on female reproductive system, and introduces the research progress of antioxidants, probiotics, vitamins and traditional Chinese medicine on alleviating the effects of BPA on reproductive system. However, the clinical application of related drugs still needs the support of evidence-based medical evidence.

Key words: Environmental pollutants, Endocrine disruptors, Femininity, Reproductive health, Drug therapy, Bisphenol A

CHANG Xiao-ying, SHEN Hao-fei, YU Xiao, ZHANG Xue-hong. Research Progress of Bisphenol A on Female Reproductive Function Injury and Drug Intervention[J]. Journal of International Reproductive Health/Family Planning, 2023, 42(1): 50-53.

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