Abstract: Maternal鄄fetal interface is the position that mother makes direct contact with her fetus.
There are complex crosstalks between the mother and the fetus. The complicated network among cells,
cytokines and extra鄄cellular matrix forms a specific state of maternal鄄fetal immune tolerance, which maintains
normal pregnancy. As a specific subset of T cells, TCR酌啄T cell is an important kind of immune cells residing
in mucosal and epithelial tissues. TCR酌啄T cells play a role in mucosal immunity. TCR酌啄T cells at maternal鄄
fetal interface have important implications for maintaining maternal鄄fetal immune tolerance. Hence, TCR酌啄T
cells are highly relevant with normal pregnancy and recurrent spontaneous abortion（RSA）.

Key words: Receptors, antigen, T-Cell, gamma-delta, Maternal-fetal exchange, Immunme tolerance, Pregnancy, Abortion, spontaneous