国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2013, Vol. 32 ›› Issue (3): 198-202.

• 综述 • 上一篇    下一篇

青春期多囊卵巢综合征的诊疗进展

赵楠楠, 崔毓桂, 刘嘉茵   

  1. 210029 南京医科大学第一附属医院生殖医学科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-05-15 发布日期:2013-05-15
  • 通讯作者: 刘嘉茵

The Diagnosis Criteria and Treatment of Polycystic Ovary Syndrome in Adolescents

ZHAO Nan-nan，CUI Yu-gui，LIU Jia-yin   

  1. State Key Laboratory of Reproductive Medicine，First Affiliated Hospital，Nanjing Medical University，Nanjing 210029，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-05-15 Online:2013-05-15
  • Contact: LIU Jia-yin

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摘要： 青春期多囊卵巢综合征（polycystic ovary syndrome，PCOS）的诊断标准仍存在争议，越来越多的学者赞成使用鹿特丹标准，前提是同时具备3个条件：稀发排卵或不排卵、高雄激素血症、超声下卵巢多囊样改变。对于青春期PCOS患者，如3个条件中只满足2个就做出诊断可能导致诊断过度。代谢综合征和睡眠障碍在青春期PCOS患者中发生率较高，并长期对患者健康造成影响。应采取综合治疗，包括调整生活方式，药物治疗是针对胰岛素抵抗及代谢功能障碍，常使用胰岛素增敏剂。综述青春期PCOS诊断与治疗的进展。

关键词: 青春期, 胰岛素抗药性, 多囊卵巢综合征, 诊断, 治疗

Abstract: The diagnosis criteria of adolescent polycystic ovary syndrome（PCOS） remains controversial. There is growing support for the Rotterdam criteria，to fit all three criteria：oligoovulation or anovulation,hyperandrogenism and polycystic ovaries on pelvic ultrasonography. The adolescent PCOS may be over-diagnosed by the standard ′two of three′ criteria. The rates of metabolic syndrome and sleep disorders are higher in those patients with the adolescent PCOS，which likely have implications on long-term health. The lifestyle modification should be included in the comprehensive treatment for the adolescent PCOS, such as diet，exercise and behavioral changes. Medicines are used to treat insulin resistance and metabolic dysfunction, such as insulin sensitizers.

Key words: Puberty, Insulin resistance, Polycystic ovary syndrome, Diagnosis, Therapy