国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2018, Vol. 37 ›› Issue (1): 45-48.

• 论著 • 上一篇    下一篇

产前贮存式自体采血对妊娠结局的影响

乐江华，唐桂艳，何燕芳，彭凌湘   

  1. 541001  桂林医学院附属医院产科
  • 收稿日期:2017-05-22 修回日期:2017-12-16 出版日期:2018-01-15 发布日期:2018-02-02
  • 通讯作者: 彭凌湘，E-mail：1713661738@qq.com E-mail:1713661738@qq.com
  • 基金资助:
    广西壮族自治区卫生和计划生育委员会自筹经费科研课题项目（Z2016393）

Effects of Predeposit Autologous Blood Donation on the Pregnancy Outcome of Pregnant Women

LE Jiang-hua, TANG Gui-yan, HE Yan-fang, PENG Ling-xiang   

  1. Department of Obstetrics, Affiliated Hospital of Guilin Medical University, Guilin 541001, Guangxi Zhuang Autonomous Region, China
  • Received:2017-05-22 Revised:2017-12-16 Published:2018-01-15 Online:2018-02-02
  • Contact: PENG Ling-xiang, E-maiｌ：1713661738@qq.com E-mail:1713661738@qq.com

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摘要： 目的：探讨产前贮存式自体采血（PABD）对孕妇妊娠结局的影响。方法：选取2015年1—12月在桂林医学院附属医院产科定期产检并分娩，同时符合PABD适应证的孕妇404例，其中进行自体采血者为研究组共203例，未进行自体采血者为对照组共201例，比较2组孕妇产后24 h出血量、新生儿出生体质量及Apgar评分、产后24 h血红蛋白（Hb）、血细胞比容（HCT）、血小板计数（PLT）、凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）情况；同时分析研究组采血前及采血后7 d，Hb、HCT、PLT、PT、APTT及FIB的变化情况。结果：2组孕妇的年龄，孕龄，产前Hb、PLT、HCT、PT、APTT及FIB比较，差异均无统计学意义（P＞0.05）。研究组与对照组的妊娠结局及各项血液指标比较显示，2组产后24 h出血量、新生儿出生体质量、1分钟Apgar评分、5分钟Apgar评分及Hb、PLT、HCT、PT、APTT、FIB情况比较，差异均无统计学意义（P＞0.05）。研究组采血后7 d的Hb、HCT、PLT、PT、APTT及FIB与采血前比较，差异均无统计学意义（P＞0.05）。结论：产前PABD对孕妇妊娠结局无不良影响，在产妇需要时能及时提供经济、有效的自体血液。

关键词:   输血, 自体, 产后出血, 妊娠结局, 孕妇

Abstract: Objective：To evaluate the effects of predeposit autologous blood donation (PABD) on the pregnancy outcome of pregnant women. Methods: A total of 404 pregnant women in our department of obstetrics from January to December 2015, who were in accordance with the PABD indications, were included in this study. There were 203 pregnant women undergoing PABD (the research group, n=203), and 201 pregnant women not enrolling in PABD (the control group, n=201). The postpartum haemorrhage volume in 24 hours, neonatal birth weight, Apgar score, 24 hours postpartum hemoglobin (Hb), hematocrit (HCT), blood platelet count (PLT), prothrombin time (PT), activated partial thrombopastin time (APTT) and fibrinogen (FIB) were recorded and analyzed. The Hb、HCT、PLT、PT、APTT、FIB before PABD and 7 days after PABD in the research group were analyzed too. Results: There were no significant differences between the two groups in the maternal age, gestational age, the prenatal Hb, PLT, HCT, PT, APTT and FIB (all P＞0.05). There were no significant differences between the two groups in the 24 hours postpartum haemorrhage volume, birth weight, 1 minute Apgar score, 5 minutes Apgar score, Hb, PLT, HCT, PT, APTT and FIB (all P＞0.05). In the research group, the Hb, HCT, PLT, PT, APTT and FIB were not significantly changed after 7 days of PABD (all P＞0.05). Conclusions: There was no adverse outcome after PABD in this study. PABD is a safe, economic and effective way for those pregnant women to get timely autologous blood when they are in need.

Key words: Blood transfusion, autologous, Postpartum hemorrhage, Pregnancy outcome, Pregnant women