关键词: 抗苗勒管激素, 多囊卵巢综合征, 排卵, 诊断

Abstract: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. It was showed that the level of AMH（Anti-Mullerian Hormone） is closely related to the pathophysiology process of PCOS. AMH may reflect the number of antral follicles, but also the dynamic interaction among various factors such as ovulation disorders, metabolic abnormalities, genetic characteristics etc. In clinical practice, AMH could be used to replace polycystic ovary morphology as one of the indicators of PCOS diagnosis criteria. Additionally, it also plays a role in the differential diagnosis between PCOM and PCOS, evaluation of the severity, prediction of the prognosis and the selection of treatment protocol of PCOS. Based on the present research, AMH could reach the preferable specificity and sensitivity with the level over 5 ng/mL or 35 pmol/L when used in the diagnosis of PCOS. AMH could be used as a potential indication in the diagnosis of PCOS although there was not the consensus, and the confounding factors were not fully excluded in those published clinical trials.

Key words: Anti-mullerian hormone, Polycystic ovary syndrome, Ovulation, Diagnosis