国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2020, Vol. 39 ›› Issue (2): 101-103.

• 论著 • 上一篇    下一篇

低体质量对体外受精-胚胎移植妊娠结局的影响

许月明，张杰，尹力，罗卓野，郝桂敏   

  1. 050000 石家庄，河北医科大学第二医院生殖医学科
  • 收稿日期:2019-10-11 修回日期:2019-11-21 出版日期:2020-03-15 发布日期:2020-03-15
  • 基金资助:
     

Impact of Low Body Mass on IVF-ET Outcome

XU Yue-ming，ZHANG Jie，YIN Li，LUO Zhuo-ye，HAO Gui-min   

  1. Department of Reproductive Medicine，The Second Hospital of Hebei Medical University，Shijiazhuang 050000，China
  • Received:2019-10-11 Revised:2019-11-21 Published:2020-03-15 Online:2020-03-15
  • Supported by:
     

PDF (PC)

8983

摘要： 目的：旨在评估低体质量对中国女性体外受精-胚胎移植（IVF-ET）新鲜周期妊娠率及活产率的影响。方法：回顾性研究2013年1月—2018年10月于河北医科大学第二医院生殖中心首次接受IVF/胞浆内单精子注射（ICSI）助孕的新鲜周期共8 171个周期。其中，低体质量组[体质量指数（BMI）＜18.5 kg/m2]共774个周期，正常体质量组（BMI 18.5～23.9 kg/m2）共7 397个周期。结果：低体质量组患者的生化妊娠率和种植率低于正常体质量组（均P＜0.05），但2组的临床妊娠率、流产率、活产率、早产率和足月产率比较，差异均无统计学意义（均P＞0.05）。结论：低体质量可能对人类辅助生殖技术（ART）新鲜周期的妊娠结局存在负面影响。

关键词: 低体重；, 人体质量指数；, 体外受精；, 胚胎移植；, 妊娠率；, 活产

Abstract: Objective: To evaluate the effects of low body mass index (BMI) on in vitro fertilization-embryo transfer (IVF-ET) outcomes in fresh transfer cycles. Methods：A total of 8 171 cycles with conventional stimulation and fresh transfer in our IVF/ＩＣＳＩ center from January 2013 to October 2018 were included. Patients with BMI<18.5kg/m2 were considered to be underweight (n=774), and patients with normal BMI (18.5-23.9 kg/m2) were used as the control (n=7 397). Results：The biochemical pregnancy rate and implantation rate of the low BMI group were significantly lower than those of the control group (P＜0.05). There were no significant differences in the clinical pregnancy rate, early abortion rate and live birth rate between the two groups(P＞0.05). Conclusions：Low BMI is a negative factor of ART fresh transfer cycles.

Key words: Low body weight；, Body mass index；, Fertilization in vitro；, Embryo transfer；, Pregnancy rate；Live birth

中图分类号: