国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2012, Vol. 31 ›› Issue (5): 354-358.

• 热点问题 • 上一篇    下一篇

对植入前遗传学诊断的不同接受程度及伦理争论

杨琨,张云山   

  1. 300100 天津市中心妇产科医院生殖医学中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-09-15 发布日期:2012-09-15
  • 通讯作者: 张云山

Acceptability and Ethical Debate about Preimplantation Genetic Diagnosis

YANG Kun，ZHANG Yun-shan   

  1. Center for Reproductive Medicine，Tianjin Central Hospital of Gynecology Obstetrics，Tianjin 300100，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-09-15 Online:2012-09-15
  • Contact: ZHANG Yun-shan

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摘要： 植入前遗传学诊断（PGD）自1990 年第一次应用于患有肾上腺脑白质不足和神经发育迟滞伴性遗传的两对夫妇之后，逐步得到推广。然而其伴随的争议也不绝于耳。目前对于PGD 的医学应用已得到世界各国广泛认可，而对于其非医学应用是否可被社会所接受还存在广泛的伦理学争议。针对PGD 技术的不同接受程度及其引起的部分热点伦理问题进行归纳总结，希望为考虑进行PGD 的患者及临床医生提供参考。

关键词: 植入前诊断, 遗传学, 伦理学, 胚胎结构

Abstract: Preimplantation genetic diagnosis （PGD）was firstly applied in 1990 in two couplesdiagnosed as adrenoleukodystrophy and X-linked mental retardation. It is widely used now in ART. However，There is continuous controversy about PGD. The medical application of PGD is widely acceptable，but its application for the non-medical purposes is still immersed in ethical controversy. In this paper，we reviewed the different acceptability and ethical issues of PGD which provide references for both patients and doctors.

Key words: Preimplantation diagnosis, Genetics, Ethics, Embryo