Effect of Circadian Rhythm Disorder on Ovarian Function

doi:10.12280/gjszjk.20220089

Abstract

Abstract:

Circadian rhythm as an endogenous timing mechanism regulates the sleep, diet and reproductive rhythm of human body. With the changes of life and work patterns, the disorder of circadian rhythm has become a health problem of general concern. Ovarian function reflects the growth and development ability of basic follicles in ovarian cortex, including the number and quality of follicles, and reflects women′s reproductive potential. More and more studies have shown that there is a correlation between circadian rhythm and ovarian function. Circadian rhythm disorder affects ovarian function by changing the secretion of reproductive hormones, ovulation, the number of oocytes, the level of melatonin and the expression of clock genes. This review expounds the influence of circadian rhythm disorder on ovarian function, so as to provide ideas for clinical research and diagnosis and treatment.

Key words: Circadian rhythm, Ovarian reserve, Gonadal steroid hormones, Ovulation, Oocytes, Melatonin

WANG Zi-xin, SONG Jia-yi, XIA Tian. Effect of Circadian Rhythm Disorder on Ovarian Function[J]. Journal of International Reproductive Health/Family Planning, 2022, 41(4): 317-321.

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