Abstract:

To report a case of a 53-year-old woman who had giant uterine lipoleiomyoma and family history of lipoma. This patient had progressively enlarged uterine fibroids for 7 years. The pelvic examination of magnetic resonance imaging suggested the possibility of a giant uterine lipoleiomyoma. Tracing the family history, both her grandmother and father had multiple lipomas. After admission, the total hysterectomy and double adnexectomy was performed. During the operation, the size of solid tumors from the lower segment of the anterior wall of the uterus to the cervix was 18 cm×12 cm×12 cm, the cut surface of tumor was light yellow, with the fatlike changes, elasticity in the texture, and greasy feeling. The white diaphragm was found to divide the tumor into two parts. Postoperative pathology showed the uterine lipoleiomyoma. The incidence of uterine lipoleiomyoma is low, and most patients are asymptomatic or have atypical symptoms, making them easy to misdiagnose. Estrogen deficiency and metabolic disorders are risk factors for its development. The post -menopausal women with the combined metabolic disorders need to be particularly alert to the development of this disease. There are no standardized treatments. Those asymptomatic patients can be treated conservatively, while symptomatic patients are often treated surgically, with the surgical option being considered on a case-by-case basis. Although it is a benign tumor, it has a risk of malignant transformation and probability of combining with gynecological malignancies, it is necessary to have the close follow-up after operation.

Key words: Uterine neoplasms, Uterus, Leiomyoma, Lipoma, Case reports