Journal of International Reproductive Health/Family Planning

Journal of International Reproductive Health/Family Planning ›› 2010, Vol. 29 ›› Issue (3): 232-234.

• 综述 • Previous Articles     Next Articles

Progress in Non-genomic Action of Progesterone

PIAO Shu-hua;Yang Qing   

  1. The Affliated Hospital of Research Institute for Family Planning of Liaoning Province,Shenyang 110031,China (PIAO Shu-hua);The Affliated Shengjing Hospital of China Medical University,Shenyang 110004,China (Yang Qing).
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-05-15 Online:2010-05-15

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Abstract: Progesterone can modulate the transcription of genes through the binding to nuclear-localized receptor. However, progesterone can also exert fast, nontranscriptional effects through the binding either to the classical nuclear receptor or the progesterone membrane receptor. The research in non-genomic
action of progesterone makes it easier to understand many physical changes in animal and human body，and it also open a new way to explain and treat the hormone-depanded malignant tumor.

Key words: Progesterone, Membrane receptor, Non-genomic action