Journal of International Reproductive Health/Family Planning ›› 2021, Vol. 40 ›› Issue (6): 524-528.doi: 10.12280/gjszjk.20210105

• Review • Previous Articles    

Progress on Diagnosis and Treatment of Ovarian Immature Teratoma

WANG An-sheng, DU Yuan-yuan, YANG Yang()   

  1. Department of Obstetrics and Gynecology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
  • Received:2021-03-10 Published:2021-11-15 Online:2021-11-30
  • Contact: YANG Yang E-mail:yangyang@hrbmu.edu.cn

Abstract:

Immature teratoma of the ovary is a germ cell tumor of the ovary, which is most frequent in women of childbearing age. It is very easy to relapse and metastasize, but the malignant degree can be reversed after recurrence by reoperation. Its origin is thought to be related to meiotic errors and epigenetic disorders. The symptoms and signs of immature teratoma of the ovary are lack of specificity. In addition to the traditional examination methods, neuronspecific enolase test, 18F-FDG PET/CT and other examination methods have been approved. It is a relatively rare disease, so there is not a clinical guideline for the treatment of ovarian immature teratoma and follow-up management in those adult and child patients. The current mainstream treatment is surgery, not chemotherapy unless it has to be, and to protect the fertility as far as possible. Due to its relatively easy relapse, postoperative follow up is very important. The follow up frequency should be the same as other malignant tumors. Growing teratoma syndrome is a relatively few complication of ovarian immature teratoma. Surgery is the main treatment method for it, and targeted drug therapy also has some progress. The research progress of the source, diagnosis, treatment and complications of ovarian immature teratoma in recent years was reviewed in order to provide a reference for clinical diagnosis and treatment.

Key words: Ovarian immature teratoma, Teratoma, Ovarian Neoplasms, Diagnosis, Therapy