Clinical Research Progress of Vulvar Lichen Sclerosus

doi:10.12280/gjszjk.20240048

Abstract

Abstract:

Vulvar lichen sclerosus (VLS) is a chronic inflammatory skin disease with female vulvar itching as the main clinical manifestation. It mainly affects the female anogenital area, such as the labia and the perianal region. VLS can affect women of all ages, but predominantly pre-pubertal girls and post-menopausal women present to hospital with persistent vulvar itching, burning pain or discomfort during intercourse. The exact pathogenesis of VLS is still unknown. Genetic, metabolic abnormalities, autoimmune and other factors may be involved. If the lesions are not treated effectively, they can eventually progress to irreversible anatomical changes in the vulva and malignant tumors, seriously endangering the physical and psychological health of the patient. According to the severity of VLS, the individualized treatment should be adopted, mainly including psychological counseling, physical intervention and surgical treatment.

Key words: Vulvar lichen sclerosus, Pruritus vulvae, Etiology, Diagnosis, Therapy

CHENG Shi-yu, SHI Jie, LI Yan-li, GAO Han. Clinical Research Progress of Vulvar Lichen Sclerosus[J]. Journal of International Reproductive Health/Family Planning, 2024, 43(3): 260-264.

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