Abstract: Objective: To discuss the treatment and follow-up strategy of atypical polypoid adenomyoma (APA) based on 9 cases and a mini review. Methods: The clinical data of 9 cases with APA admitted in our hospital (2008 to 2016) were retrospectively analyzed. Results: The average age of 9 cases is 37.4 (20-50), years old. Among 9 cases, 3 cases were simple APA, 1 case was APA complicated with endometrioid adenocarcinoma, 1 case was APA complicated with endometrial complex atypical hyperplasia; 1 case was APA ended up with endometrial complex atypical hyperplasia; 1 case was endometrial complex atypical hyperplasia，ended up with APA complicated with endometrial complex atypical hyperplasia; 1 case was APA ended up with endometrial complex hyperplasia; 1 case was APA complicated with endometrial complex hyperplasia. 3 cases were treated with fractional curettage, and 6 cases with hysteroscopic resection as the initial treatment. All cases underwent the follow-up visit 45.5(3-103) months, and no relapse and canceration were observed until January 2017. 3 cases of APA with primary infertility didn′t achieve their pregnances. Conclusions: Although APA is a benign disease, it should be treated actively because of its potential malignancy. The treatment strategy is related to many factors, such as age, the architectural index of the gland, endometrium situation and fetility demand.

Key words:  Atypical polypoid adenomyoma, Hysteroscopes, Progestins, Therapy, Follow-up studies