Abstract: European Society of Human Reproduction and Embryology (ESHRE) proposed the standard definition of the effective treatment with assisted reproductive technology (ART) in 2002: live birth and a single healthy baby. The best way to reduce multiple pregnancies, which is one of the serious complications of ART, is the strategy of single blastocyst transfer (SBT). Theoretically, SBT can avoid the possibility of dizygotic twins. However, the SBT without any selection in patient and embryo may result in the reduction of pregnancy rate and live birth rate, but also increase economic and time cost as well as mental pressure. Therefore, the selective single blastocyst transfer (eSBT) should be recommended in those suitable patients. The consultation with respect to the factors related with the clinical outcome and live birth of SBT may be helpful to evaluate effectively the patients′ status and the success rate of SBT, so as to accept SBT more easily, which eventually help them bring a healthy baby home as soon as possible.

Key words:  Embryo transfer, Blastocyst inner cell mass, Trophoblasts, Pregnancy rate, Birth rate, Therapy