Abstract: The peripheral vaginal atrophy-related sexual dysfunction (FDS) in perimenopausal and postmenopausal women is a common disease that can affect the quality of life of many perimenopausal and postmenopausal women. However, its awareness and treatment are very limited. Those perimenopausal women experience the gradually declined ovarian function, with endocrine variation, and decreased estrogen. At the same time, their vaginal mucosa atrophied, elasticity and lubrication will be weakened. Therefore, the prevalence of sexual dysfunction was increased in perimenopausal and postmenopausal women. It was reported that FSD was closely related to age, poor lifestyle, endocrine factors, alcohol consumption, chronic diseases, dystocia, divorce and other factors. The treatment of the vulvovaginal ■ FSD in those perimenopausal and postmenopausal women should be based on their symptoms and main risk factors, in order to improve the quality of life. This paper reviewed the risk factors and treatment of vulvovaginal atrophy-related FSD in those perimenopausal and postmenopausal women.

Key words: Vulva, Vagina, Atrophy, Perimenopause, Postmenopause, Sexual dysfunction, physiological