Abstract: Adenomyosis (AD) as a benign uterine disease is characterized by ectopic endometrial glands and stroma in the myometrium. The pathomechanism of AD is still unclear. This disease often occurs in women of childbearing age from 30 to 50 years old. Clinical manifestations may be asymptomatic, hypogastralgia or abnormal uterine bleeding. Transvaginal ultrasound and magnetic resonance imaging are helpful in the diagnosis of AD. Although diagnostic methods have been improved, there is not a uniform classification of AD. The patients′ understanding is still insufficient. Currently, the therapy drug for this disease includes gonadotropin-releasing hormone agonist and levonorgestrel intrauterine sustained release system. The conservative surgery includes uterine artery embolization, lesion resection and high intensity focused ultrasound. Studies have shown that AD has a negative impact on female fertility, with high risks of miscarriage and obstetric complications. After the effective treatment, the fertility can be improved. It is necessary to develop a lifelong health management plan for those AD patients.

Key words: Adenomyosis, Infertility, female, Diagnosis, Therapy