A Case Report of Early Embryonic Arrest due to TUBB8 Mutation

doi:10.12280/gjszjk.20210068

Abstract

Abstract:

The mutation in TUBB8 gene (c.208C>T/p.Pro70Ser) was found in a patient with early embryonic arrest after repeated IVF/ICSI. The association betweenTUBB8 mutation and early embryonic arrest was further explored. This study provides more possibilities for the diagnosis and treatment of patients with recurrent implant failure.

Key words: Genes, Mutation, Embryonic development, TUBB8 gene, Fertilization in vitro, Sperm injections, intracytoplasmic

LI Wen-shu, LIU Xue-mei. A Case Report of Early Embryonic Arrest due to TUBB8 Mutation[J]. Journal of International Reproductive Health/Family Planning, 2021, 40(4): 303-305.

Figures/Tables 3

References 13

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周期	助孕方式	COH方案	获卵数	MⅡ卵数	GV卵数	D2受精卵数	D3胚胎形成数	移植胚胎数
第1周期	IVF	拮抗剂方案	4	2	1	1	2	0
第2周期	IVF	卵泡期长效长方案	8	5	3	0	2	2
第3周期	ICSI	长方案	5	5	0	5	4	2
第4周期	ICSI	拮抗剂方案	8	8	0	8	7	2

周期	助孕方式	COH方案	获卵数	MⅡ卵数	GV卵数	D2受精卵数	D3胚胎形成数	移植胚胎数
第1周期	IVF	拮抗剂方案	4	2	1	1	2	0
第2周期	IVF	卵泡期长效长方案	8	5	3	0	2	2
第3周期	ICSI	长方案	5	5	0	5	4	2
第4周期	ICSI	拮抗剂方案	8	8	0	8	7	2

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