Abstract:

Objective： To understand the prevalence and epidemiological characteristics of perinatal birth defects in Hebei Province from 2017 to 2021. Methods： The data were from the birth defect information monitoring system of Hebei Center for Women and Children′s Health from 2017 to 2021. The system includes 22 monitoring points (hospitals) distributed in various cities of Hebei Province. Results： There were 200 146 hospitalized deliveries in Hebei province, of which 8 908 were birth defects, and the incidence of birth defects was 445.08/10 000. The perinatal survival rate of birth defects was showed an upward trend. The top 10 reported cases were congenital heart disease, cleft palate/lip palate, polydactyls and syndactyls, other abnormalities of the outer ear, fetal chromosomal abnormalities, polydactyls and syndactyls, hydrocephalus, hypospadias, congenital malformations of the digestive system and clubfoot. The incidence of perinatal birth defects is different in different regions. The incidence of birth defects in urban areas was higher than that in rural areas; the incidences of birth defects in women aged <18 years and ≥35 years were higher than that in women aged 18-35 years; and the incidence of perinatal birth defects in menpara women was higher than that in primipara women. The incidence of perinatal birth defects in males was higher than that in females (P<0.001). Conclusions： There were the regional, urban and age differences in the incidence of birth defects in Hebei province. It is necessary to carry out eugenics′ education for pregnant women with high risk factors, and publicize the importance of health care before and during pregnancy.

Key words: Hebei, Congenital abnormalities, Epidemiologic studies, Perinatal infant, Incidence