Abstract: This commentary focused on the existing controversies about male climacteric and male
climacteric syndrome, discussing on the following major topics one by one: definition and scope of male
climacteric health, testosterone decline and male climacteric syndrome, as well as the rationale of testosterone
supplement treatment. It is recommended to develop a whole lifespan systematic analysis and comprehensive
intervention strategy for male climacteric health care and health promotion.

Key words: Male climacteric, Male climacteric syndrome, Late-onset hypogonadism, Testosterone supplement treatment, Male climacteric health