Abstract: Objective: To compare the clinical efficiencies of three anesthetic techniques used in the transvaginal ultrasound-guided oocyte retrieval. Methods：From December 2011 to March 2012 in our Center，462 patients undergoing IVF-ET were divided into three groups according to anesthetic techniques during oocyte retrieval，group A（227 cases） used Dolantin （ｉ．ｍ．） only, group B（54 cases） used acupuncture anesthesia，and group C（181 cases） used Propofol （ｉ．ｖ．）． The anesthesia effects and adverse effects were evaluated. Results：There were higher oocyte retrieval rate in group C than the other groups（P＜0.05），but there were no significant differences in clinical pregnancy rate and miscarriage rate among three groups（P＞0.05）. The analgesic effects in three groups were similar, but the adverse effects in the group B and C, such as nausea and sweating，were lower（P＜0.05） than those in group A. Conclusions：Acupuncture anesthesia and Propｏｆｏｌ （ｉ．ｖ．） can reduce pain intensity and adverse effects in patients undergoing transvaginal oocyte retrieval, although treatments do not affect the clinical pregnancy rate and the abortion rate in IVF-ET.

Key words: Acupuncture anesthesia, Fertilization in vitro, Embryo transfer, Anesthesia, intraveneous, Oocyte retrieval