Objective: To explore the application of mindfulness-based interventions (MBIs) in the patients undergoing in vitro fertilization-embryo transfer (IVF-ET), with a scoping review. Methods: Following the Joanna Briggs Institute methodology for scoping reviews, we systematically searched PubMed, Web of Science, Embase, Cochrane Library, CINAHL, CNKI, WanFang Data, VIP and CBM databases. Two researchers independently performed literature screening and data extraction, followed by synthesis and analysis of included studies. Results: Twenty-two studies were included. The intervention modalities included mindfulness-based stress reduction (MBSR), mindfulness-based cognitive therapy (MBCT), mindfulness-based yoga, mindfulness-based childbirth and parenting (MBCP), and acceptance and commitment therapy (ACT). The delivery formats included in-person training, online training and hybrid approaches. Most interventions were administered weekly (1-2 h/session). Most studies have shown that mindfulness intervention can alleviate anxiety and depression, significantly reduce the symptoms such as hostility and interpersonal sensitivity, and effectively lower the sense of stigma and enhance the happiness index and marital satisfaction, while mindfulness intervention can improve the sleep quality and physical comfort, as well as the quality of life and marriage. Meanwhile, most of IVF-ET patients expressed their satisfaction and recognition of the mindfulness intervention course. Conclusions: Preliminary evidence supports the diversity, integrative potential, efficacy and feasibility of MBIs in IVF-ET patients. Future research should optimize the personalized intervention protocols, explore the web-based remote delivery strategies, and further validate the long-term effect across multidimensional outcomes including psychological well-bing, sleep quality, mindfulness levels, and quality of life in IVF-ET patients.
