国际生殖健康/计划生育 ›› 2012, Vol. 31 ›› Issue (1): 17-19.

• 热点问题 • 上一篇    下一篇

乙型肝炎患者实施辅助生殖技术中病毒传播的风险与防范


徐 仙, 宋梦玲
  

  1. 750004 银川,宁夏医科大学总医院生殖医学中心,生育力保持省部共建教育部重点实验室,宁夏回族自治区生殖与遗传重点实验室
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-01-15 发布日期:2012-01-15

肝炎,乙型,慢性;肝炎病毒,乙型;肝炎表面抗原,乙型;生殖技术,辅助;疾病传播,垂直;阻断疗法

XU Xian, SONG Meng-ling   

  1. Center for Reproductive Medicine, the General Hospital of Ningxia Medical University, Key Laboratory of Fertility Preservation and Maintenance Ningxia Medical University, Ministry of Education, Key Laboratory of Reproduction and Genetics in Ningxia, Yinchuan 750004, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-01-15 Online:2012-01-15

摘要: 慢性乙型肝炎(简称乙肝)是中国第一大传染病,严重危害健康和威胁生命,受到广泛关注。随着乙肝患者发病率的上升及辅助生殖技术(ART)的迅猛发展,乙型肝炎病毒(HBV)感染者实施ART过程中HBV的传播成为热议话题。对慢性乙肝患者实施ART,因操作不当及管理不严,有发生交叉感染或院内感染的危险,既可能将病毒传播给正常者的配子和胚胎,也可能将病毒传播给医疗技术人员。然而,科学合理地ART可降低病毒传播给子代的风险。综述HBV感染者的ART传播风险和防范措施,为预防病毒传播和医源性感染提供科学依据。

关键词: 肝炎, 乙型, 慢性, 肝炎病毒, 乙型, 肝炎表面抗原, 乙型, 生殖技术, 辅助, 疾病传播, 垂直, 阻断疗法

Abstract: Chronic hepatitis B, the largest infectious disease in China which damaged to health seriously,should be given wide attention. With the rising incidence of hepatitis B patients and the rapid development of assisted reproductive technology(ART), the transmission of hepatitis B virus during ART become a hot topic. when ART was applied in those chronic hepatitis B patients, there was probability of cross-infection or the risk of nosocomial infection because of improper operation and poor management. Hepatitis B virus could spread to both normal gametes and embryos, even transmit to medical technicians. However, scientific and rational implementation of ART can reduce the risk of virus transmission to progeny. In this review, we discussed the risk and prevention of transmission of hepatitis B virus in ART.

Key words: Hepatitis B, chronic, Hepatitis B virus, Hepatitis B surface antigens, Reproductive techniques, assisted, Disease transmission, vertical, Withholding treatment