国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2015, Vol. 34 ›› Issue (1): 43-47.

• 论著 • 上一篇    下一篇

育龄妇女受教育程度与其对叶酸补充认知及服用关系的Meta分析

王宏伟，茅群霞，刘庆   

  1. 100048 北京，中国劳动关系学院（王宏伟）；国家人口计生委科学技术研究所（茅群霞，刘庆）
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-01-15 发布日期:2015-01-15
  • 通讯作者: 刘庆

Relationship between Educational Level and Folic Acid Supplementation in Child-bearing Chinese Women：A Meta-analysis

WANG Hong-wei，MAO Qun-xia，LIU Qing   

  1. China Institute of Industrial Relations，Beijing 100048，China（WANG Hong-wei）；National Research Institute for Family Planning，Beijing 100081，China（MAO Qun-xia，LIU Qing）
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-01-15 Online:2015-01-15
  • Contact: LIU Qing

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摘要： 目的：利用已发表文献，采用荟萃分析方法分析我国育龄妇女受教育程度与其对叶酸补充的认知及服用情况的关系。方法：分别在Pubmed采用“folic acid”、“pregnancy”和“China”等关键词组合进行检索；在中国生物医学文献服务系统（Sinomed）、中国期刊全文数据库（CNKI）、维普中文期刊全文数据库（VIP）等数据库中采用“叶酸”、“妇女”等关键词组合检索相关文献，检索所有2014年4月19日及此前的相关文献，并对文章的参考文献也进行了检索。纳入标准为：观察性研究；包含受教育程度与育龄妇女对叶酸补充的认知或服用关系信息；研究对象为中国育龄妇女。结果：共获得中英文全文文献436篇，其中中文339篇、英文97篇。最终纳入符合标准的文献15篇。采用随机效应模型进行荟萃分析，以受教育水平为初中及以下者为对照，其余调查对象知晓叶酸的OR值及其95%CI分别为：高中/中专 2.12（1.65，2.72）、大学及以上6.24（4.24，9.19）；调查对象服用叶酸的OR值及其95%CI分别为：高中/中专1.63（1.39，1.93）、大学及以上3.48（2.35，5.16），差异均有统计学意义。结论：我国育龄妇女受教育水平与其对叶酸的认知及服用叶酸有关。应重点加强受教育水平较低的育龄妇女对叶酸的认知和正确服用的相关教育，以进一步降低新生儿神经管畸形发生的概率，提高我国母婴健康水平。

关键词: 叶酸, 教育程度, Meta分析

Abstract: Objective：To investigate the relationship between the educational level of Chinese child-bearing women and their knowledge on supplementation of folic acid, by the Meta-analysis of the published data. Methods：Searches were done by using Pubmed (up to Apr. 19th, 2014) with English, and Sinomed, CNKI and VIP with Chinese. The search term combined with the keywords as follows: "folic acid", "pregnancy" and "China" was used to search English papers, while the search term combined with the keywords as: "folic acid" and "women" was used to search Chinese papers. Studies involved in this meta-analysis were defined as the observational study, including the information about the association between the educational level of child-bearing women and their knowledge and/or supplementation of folic acid. Only Chinese women were involved in the studies. Results：A total of 436 papers including 339 Chinese papers and 97 English papers were collected. After selection according to the criterion, a total of 15 eligible studies were remained in the Meta-analysis. Random effect models were used. Meta-analysis showed that the OR values and the related 95%CIs of the knowledge on folic acid were: 2.12 (1.65, 2.72) in those women with high school/technical secondary school education, 6.24 (4.24, 9.19) in those women with at least college education, when compared with those women with less than junior middle school education; and that the OR values and the related 95%CIs of the folic acid supplementation were 1.63 (1.39, 1.93) and 3.48 (2.35, 5.16) in two groups when compared analogously. Conclusions：The knowledge and supplementation of folic acid is related to their educational level in those Chinese child-bearing women. To prevent neural tube defects and to improve the health situation of Chinese women and children, it is necessary to enhance the health education on folic acid for those women with relatively less education.

Key words: Folic acid, Educational status, Meta-analysis