妊娠合并卵巢肿瘤的诊疗进展

doi:10.12280/gjszjk.20200321

摘要/Abstract

摘要：

妊娠合并卵巢肿瘤（pregnancy associated with ovarian tumors,POT）是妊娠期较常见的并发症之一,近年来,随着产科超声的广泛应用,在妊娠期间被诊断为POT的妇女数量有所增加。POT多数为功能性囊肿,于妊娠期偶然发现并自行消退,恶性肿瘤的发生率为1%~6%,其中以无性细胞瘤最为常见。多数POT患者无特异性临床症状,少数可发生破裂、扭转等而导致急腹症。其临床诊断方式多样,影像学检查通常以超声检查作为首选,肿瘤标志物可协助评估潜在恶性风险。目前尚无POT相关的规范化诊疗准则,治疗需综合考虑母胎两方面因素,由临床医师根据孕周、肿瘤类型、疾病阶段等制定个体化方案。由于腹腔镜手术具有出血少、恢复快等优点,常作为首选手术方式。若为恶性肿瘤,可在妊娠中期开始化疗。本文就POT的诊疗进展进行综述,以期为临床治疗提供参考。

关键词: 妊娠, 妊娠并发症,肿瘤, 卵巢肿瘤, 诊断, 治疗

Abstract:

Pregnancy associated with ovarian tumors (POT) is one of the most complications of pregnancy. With the application of ultrasound in prenatal examination, more and more POT has been diagnosed during pregnancy. POT is mostly a functional cyst that discovered by chance during pregnancy and resolved spontaneously. The incidence of malignant POT is 1%-6%, among which disgerminoma is the most common. Most of POT have no specific clinical symptoms, while a few of POT can rupture, twist and so on with acute abdomen. There are various clinical diagnosis methods. Ultrasound examination is usually the first choice for imaging examination. Tumor markers can help to assess the potential malignant risk. At present, there is no standardized diagnosis and treatment guideline of POT. Both maternal and fetal factors should be taken into consideration in treatment. Clinicians should make the individual plan for each POT patient according to her gestational week, tumor type, disease stage, etc. Due to the advantages of less bleeding and faster recovery, laparoscopic surgery is preferred. This article reviews the progress of POT diagnosis and treatment in order to provide reference for clinical work.

Key words: Pregnancy, Pregnancy complications,neoplastic, Ovarian neoplasms, Diagnosis, Therapy

辛玉琦, 王晓慧. 妊娠合并卵巢肿瘤的诊疗进展[J]. 国际生殖健康/计划生育, 2021, 40(2): 167-171.

XIN Yu-qi, WANG Xiao-hui. Progress in Diagnosis and Treatment of Pregnancy Associated with Ovarian Tumors[J]. Journal of International Reproductive Health/Family Planning, 2021, 40(2): 167-171.

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