生殖相关疾病与膳食炎症指数关系的研究进展

doi:10.12280/gjszjk.20220285

摘要/Abstract

摘要：

炎症参与了多囊卵巢综合征、子宫内膜异位症、妇科肿瘤等多种疾病的发生、发展,同时也可影响男性生殖功能。饮食在调节慢性炎症中发挥重要作用。膳食炎症指数（dietary inflammation index,DII）是一种新的临床膳食评估工具,将饮食分为促炎饮食和抗炎饮食,用于评估个人膳食整体的炎症潜力。研究显示,促炎饮食与生殖相关疾病的发生风险增加有关,抗炎饮食则与生殖相关疾病的发生风险降低有关。促炎饮食及其组分可升高机体内的炎症水平,促使慢性子宫内膜炎、多囊卵巢综合征、卵巢癌及子宫内膜癌等多种疾病的发生,也可对男性精子浓度和总活力等产生影响,从而导致不孕不育。综述DII与生殖相关疾病的关系和临床机制,并从疾病的预防和控制方面提出饮食建议,以期为临床治疗和护理提供参考。

关键词: 炎症, 不育症, 生殖器疾病,女（雌）性, 弱精子症, 健康膳食, 膳食炎症指数

Abstract:

Inflammation is involved in the occurrence and development of polycystic ovary syndrome, endometriosis, gynecological tumors and other diseases, and can also affect male reproductive function. Diet plays an important role in regulating chronic inflammation. Dietary inflammation index (DII) as a new clinical dietary assessment tool is used to assess the overall inflammatory potential of an individual′s diet. DII divides the daily diet into proinflammatory diet and anti-inflammatory diet. Studies have shown that the proinflammatory diet is associated with the increased risk of reproduction-related diseases, while the anti-inflammatory diet is associated with the decreased risk of reproduction-related diseases. The proinflammatory diet and its components can increase the level of inflammation in the body, promote the occurrence of chronic endometritis, polycystic ovary syndrome, ovarian cancer, endometrial cancer and other diseases. At the same time, this kind of diet can also affect the concentration of male sperm and total motility, resulting in infertility. To review the relationship between DII and reproductive diseases and the clinical mechanism, and to put forward the dietary suggestions from the prevention and control of diseases, will provide us a reference for clinical treatment and nursing.

Key words: Inflammation, Infertility, Genital diseases, female, Asthenozoospermia, Healthy diet, Dietary inflammation index

申梦丹, 贺娟娟, 高明霞, 梁兰兰, 胡俊平. 生殖相关疾病与膳食炎症指数关系的研究进展[J]. 国际生殖健康/计划生育, 2022, 41(5): 436-440.

SHEN Meng-dan, HE Juan-juan, GAO Ming-xia, LIANG Lan-lan, HU Jun-ping. Research Progress on the Relationship between Reproductive Diseases and Dietary Inflammation Index[J]. Journal of International Reproductive Health/Family Planning, 2022, 41(5): 436-440.

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