国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2014, Vol. 33 ›› Issue (2): 128-130.

• 综述 • 上一篇    下一篇

维生素D与多囊卵巢综合征

杜旭园，顾林   

  1. 210000 南京医科大学（杜旭园）；南京医科大学附属南京市妇幼保健院（顾林）
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2014-03-15 发布日期:2014-03-15
  • 通讯作者: 顾林

Vitamin D and Polycystic Ovary Syndrome

DU Xu-yuan，GU Lin   

  1. Nanjing Medical University，Nanjing 210000，China（DU Xu-yuan）；Nanjing Maternity and Child Health Care Hospital，Nanjing Medical University，Nanjing 210000，China（GU Lin）
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-03-15 Online:2014-03-15
  • Contact: GU Lin

PDF (PC)

7545

摘要： 多囊卵巢综合征（PCOS）是以稀发排卵或不排卵和高雄激素血症为主要特征的妇科内分泌疾病。PCOS患者普遍存在维生素D缺乏，近年的临床研究显示，25-羟基维生素D水平与PCOS症状中的胰岛素抵抗、排卵障碍、月经紊乱、妊娠成功率低、多毛、高雄激素血症、肥胖及心血管发病风险增高密切相关。维生素D缺乏可能在加重PCOS症状中发挥了重要的作用，初步临床试验显示维生素D可能对PCOS有辅助治疗作用。就目前维生素D与PCOS的相关性临床试验进行综述。

关键词: 维生素D, 多囊卵巢综合征, 受体, 骨化三醇

Abstract: Polycystic ovary syndrome（PCOS） is the gynecologic endocrine diseases characterized by chronic anovulation and hyperandrogenism. The women with PCOS may be complicated with vitamin D deficiency. Many clinical trials in recent years indicated the association between 25-hydroxy vitamin D [25（OH）D] level and PCOS, including insulin resistance，ovulatory dysfunction，menstrual irregularities，low pregnancy success，hirsutism，hyperandrogenism，obesity and the elevated risk factors of cardiovascular diseases. Vitamin D deficiency may play an important role in aggravating symptoms of PCOS. The preliminary clinical data suggested the possible benefits of vitamin D supplementation in women with PCOS. This review summarized the current clinical researches on the correlation between vitamin D and PCOS．

Key words: Vitamin D, Polycystic ovary syndrome, Receptors, calcitriol