国际生殖健康/计划生育杂志 ›› 2025, Vol. 44 ›› Issue (3): 211-214.doi: 10.12280/gjszjk.20240515

• 病例报告 • 上一篇    下一篇

卵巢甲状腺肿类癌一例

袁梦, 李君芬, 吴岳霄, 杨永秀()   

  1. 730000 兰州大学第一临床医学院(袁梦,李君芬,吴岳霄);兰州大学第一医院妇产科,甘肃省妇科肿瘤重点实验室(杨永秀)
  • 收稿日期:2024-10-24 出版日期:2025-05-15 发布日期:2025-06-04
  • 通讯作者: 杨永秀,E-mail:yongxiuyang@163.com

Strumal Carcinoid Tumor of the Ovary: A Case Report

YUAN Meng, LI Jun-fen, WU Yue-xiao, YANG Yong-xiu()   

  1. The First School of Clinical Medicine of Lanzhou University, Lanzhou 730000, China (YUAN Meng, LI Jun-fen, WU Yue-xiao); Department of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Key Laboratory of Gynecological Tumor of Gansu Province, Lanzhou 730000, China (YANG Yong-xiu)
  • Received:2024-10-24 Published:2025-05-15 Online:2025-06-04
  • Contact: YANG Yong-xiu, E-mail: yongxiuyang@163.com

摘要:

卵巢甲状腺肿类癌(strumal carcinoid tumor of the ovary,SCTO)为继发于卵巢成熟畸胎瘤的一种卵巢恶性肿瘤,临床上十分罕见,其病理组织由甲状腺组织和类癌成分组成,但病因及发病机制尚不明确。患者常以腹痛就诊,需要病理组织活检和免疫组织化学检查结果才能确诊。报告1例43岁SCTO的病例,患者因腹痛、恶心呕吐就诊于外院,行妇科B超提示盆腔包块,遂行腹腔镜下右侧附件切除术,术后病理考虑SCTO。后就诊于我院,完善免疫组织化学检查,确诊为SCTO,遂行全子宫切除+左侧输卵管-卵巢切除+双侧卵巢动静脉高位结扎+右侧盆腔淋巴结切除+部分大网膜切除补充手术,术后病理未见淋巴及远处转移,未行辅助治疗,术后随访8个月未见复发及转移。SCTO早期预后较好,因此早识别、早治疗对改善患者的预后至关重要。

关键词: 卵巢, 畸胎瘤, 类癌瘤, 诊断, 治疗, 病例报告

Abstract:

Strumal carcinoid tumor of the ovary (SCTO) is an exceptionally rare malignant ovarian tumor that arises secondary to a mature ovarian teratoma. It is characterized by the presence of thyroid tissue and carcinoid components in pathological tissue. The pathogenesis of SCTO is not clear. The patients commonly present with abdominal pain, but the accurate diagnosis dependes on the histopathological evaluation and immunohistochemical analysis due to its rarity and atypical presentation. We report the case of a 43-year-old woman diagnosed with SCTO. She initially presented to an external hospital with the complaints of abdominal pain accompanied by nausea and vomiting. Gynecological ultrasound revealed a pelvic mass, and she was treated with the laparoscopic right-adnexectomy. Histopathological analysis suggested SCTO. The patient was subsequently transferred to our hospital for further treatment. The immunohistochemical analysis confirmed the diagnosis of SCTO. To ensure comprehensive treatment, a subsequent surgical procedure was performed, including total hysterectomy, left salpingo-oophorectomy, high ligation of bilateral ovarian vessels, right pelvic lymphadenectomy, and partial omentectomy. Lymphatic or distant metastasis was not found in the postoperative histopathological examination. The patient did not undergo adjuvant therapy, and remained free of recurrence and metastasis during 8 month follow-up. SCTO diagnosed at an early stage is associated with a favorable prognosis. Therefore, early recognition and timely intervention are essential to improve the outcomes of SCTO patient.

Key words: Ovary, Teratoma, Carcinoid tumor, Diagnosis, Therapy, Case reports