国际生殖健康/计划生育 ›› 2016, Vol. 35 ›› Issue (3): 229-232.

• 综述 • 上一篇    下一篇

女性生殖器官发育异常与不育

黄禾,田秦杰   

  1. 100730 中国医学科学院 北京协和医科大学 北京协和医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-05-15 发布日期:2016-05-15

Infertility and Abnormal Development of Female Reproductive System

HUANG He, TIAN Qin-jie   

  1. Department of 0bstetrics and Gynecology,Peking Union Medical College Hospital,Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100730, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-05-15 Online:2016-05-15

摘要: 女性生殖器官在形成、分化过程中,若受到某些内源性因素(如基因或染色体异常等)或外源性因素(如使用性激素类药物)的影响,原始性腺的分化、发育、内生殖器始基的融合、管道腔化和发育以及外生殖器的衍变可发生改变,导致各种女性内外生殖器官发育异常。尽管女性生殖器官发育异常发生率低,但可能从性交、排卵、受精、着床等各个方面影响患者的生殖力,导致不育。大部分患者有闭经、生殖道梗阻以及生殖障碍等临床表现。手术矫正畸形与辅助生殖技术的发展为女性生殖器官发育异常的不育患者提供了生育的可能以及新的生育途径,可达到解除梗阻、恢复解剖、促进生育和提高生命质量的目的。

关键词: 生殖器, 女(雌)性, 不育, 女(雌)性, 先天畸形, 泌尿生殖系统畸形

Abstract: The congenital anatomic disorders of the female reproductive organs occur frequently, which may be related to genetic mutation, developmental arrest, abnormal hormonal exposure, or exposure to environmental insults that exert their effects at critical stages of embryonic development. Although the genital anomalies are rare, they may affect the patients′ fecundity on sexual intercourse, ovulation, fertilization and implantation. Most of the patients present clinical manifestations of genital tract obstruction, amenorrhea and reproductive disorders. Surgical correction of deformity and assisted reproductive technology(ART) provide those infertility patients with genital anomalies new hope to bear children. The objective of treatment for those patients extends to relief the obstruction, to correct their genital anomalies, and to improve fertility and the life quality.

Key words: Genitalia, female, Infertility, female, Congenital abnormalities, Urogenital abnormalities