国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2012, Vol. 31 ›› Issue (2): 137-140.

• 综述 • 上一篇    下一篇

微量营养物质在围妊娠期中的作用

俞凌,王淑芳,姚元庆   

  1. 100853北京，中国人民解放军总医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-03-15 发布日期:2012-03-15
  • 通讯作者: 姚元庆

Function of Micronutrients in the Periconceptional Period

YU Ling，WANG Shu-fang，YAO Yuan-qing   

  1. Department of Obstetrics and Gynecology, the General Hospital of the People's Liberation Army，Beijing 100853，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-03-15 Online:2012-03-15
  • Contact: YAO Yuan-qing

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摘要： 研究已证实，微量营养元素的缺乏与高生殖风险有关，这些风险包括不孕症、胎儿发育畸形以及其他远期疾病。围妊娠期是一个很特殊的重要时期，主要包括受精、受孕、植入、胎儿器官发生和胎盘发生等几个重要阶段，且这几个阶段最有可能被微量营养元素影响。尤其是一些具有抗氧化活性的微量营养元素，可以有效阻止活性氧簇（ROS）造成的氧化损伤，从而保护围妊娠期各个阶段的胎儿和母体免受伤害，可见预防性地应用一些微量营养元素或许能够扭转不良的妊娠结局。人们应该在妊娠前掌握更多的围妊娠期健康饮食知识，也应该有更多的研究来关注围妊娠期的营养需求。重点阐述在围妊娠期中微量营养元素与各种生殖风险的关系。

关键词: 产前营养生理学, 痕量元素, 维生素类, 胚胎和胎儿发育, 妊娠结局, 活性氧

Abstract: Micronutrient deficiencies have been proved to be associated with the high reproductiverisks, such as infertility, some fetal structural defects and long-term diseases. The periconceptional period isparticularly critical stages, including fertility, conception, implantation, fetal organogenesis and placentation,which potentially affected by micronutrients. In particular，some micronutrients have antioxidant activity, sothey can effect against the oxidative damage caused by reactive oxygen species (ROS). These micronutrients protect fetus and mother in every stage of periconceptional period. So, the prophylactic use of some micronutrients may prevent adverse pregnancy outcomes. People should increase awareness of healthy diet before pregnancy. In this review, we discussed on the relationship beween some poor micronutrients and reproductive risks in the periconceptional period.

Key words: Prenatal nutrition physiology, Trace elements, Vitamins, Embryonic and fetal development, Pregnancy outcome, Reactive oxygen species