国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2011, Vol. 30 ›› Issue (2): 123-125.

• 综述 • 上一篇    下一篇

输卵管的性激素受体表达及功能

邹世恩, 张绍芬   

  1. 200011 上海， 复旦大学附属妇产科医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-03-15 发布日期:2011-03-15

The Expression and Effect of Sex Steroid Hormone Receptors in Fallopian Tube

ZOU Shi-en， ZHANG Shao-fen   

  1. Obstetrics and Gynecology Hospital of Fudan University， Shanghai 200011， China
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-03-15 Online:2011-03-15

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摘要： 输卵管妊娠是一种威胁女性生命的疾病，性激素及其受体（雌激素、孕激素和雄激素受体）对输卵管生理和病理有重要的调节作用，3类受体都在输卵管上表达，并表现出时间和区域特异性。其中雌激素受体和孕激素受体可能通过影响纤毛活性和平滑肌收缩参与输卵管妊娠的发病机制。

关键词: 受体, 雌激素, 受体, 孕激素, 受体, 雄激素, 妊娠, 输卵管

Abstract: Tubal ectopic pregnancy still remains a potentially life-threatening diseases. Sex steroid hormones and their receptors, including estrogen receptor（ＥＲ）， progesterone receptor（ＰＲ） and androgen receptor（ＡＲ）， play important roles on fallopian tubal physiology and pathology. Those receptors are expressed in the fallopian tubes， and have time and region?-characteristics. Among them， ER and PR may participate pathogenesis of tubal ectopic pregnancy through mediating ciliary activity and the tubal smooth muscle activity.

Key words: Receptors, estrogen, Receptors, progesterone, Receptors, androgen, Pregnancy, tubal