国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2015, Vol. 34 ›› Issue (2): 123-125.

• 论著 • 上一篇    下一篇

绝经症状与抑郁焦虑情绪相关性研究

成贇，郭雪桃，丛新茹，刘会平   

  1. 030001 太原，山西医科大学第一医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-03-15 发布日期:2015-03-15
  • 通讯作者: 郭雪桃

Correlation of Menopause Symptoms with Anxiety and Depression

CHENG Yun，GUO Xue-tao，CONG Xin-ru，LIU Hui-ping   

  1. Department of Obstetrics and Gynecology，The First Affiliated Hospital of Shanxi Medical University，Taiyuan 030001，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-03-15 Online:2015-03-15
  • Contact: GUO Xue-tao

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摘要： 目的：探讨不同生殖衰老阶段女性绝经症状与抑郁焦虑情绪的相关性。方法：对门诊妇女进行面对面问卷调查，内容包括一般情况、自评抑郁量表（SDS）、自评焦虑量表（SAS）、改良Kupperman评分表。共372例患者入选。根据STRAW+10分期系统分为生育期晚期组（105例）、围绝经早期组（110例）、围绝经晚期组（84例）和绝经后早期组（73例）。结果：4组患者绝经相关症状严重程度、SDS、SAS、Kupperman评分和抑郁焦虑的发生率比较差异有统计学意义（均P＜0.05）。潮热出汗、心悸症状与抑郁、焦虑情绪有关，性交痛、阴道干涩与焦虑情绪有关。Kupperman评分与SDS、SAS评分呈弱相关（r分别为0.465、0.421，P＜0.001，r2分别为0.22和0.18）。SDS评分与SAS评分呈正相关（r=0.801，P＜0.001，r2=0.64）。结论：40岁后育龄期晚期妇女可出现绝经症状及抑郁焦虑情绪，且随着生殖衰老进展有增加趋势，抑郁和焦虑互相影响。

关键词: 绝经期, 围绝经期, 绝经后期, 抑郁, 焦虑

Abstract: Objective：To explore the association between menopause symptoms and depression and anxiety in those women at different aging stages. Methods：The questionnaire was designed for those outpatient women, which included demographic characteristics, modified Kupperman score and self-rating depression/anxiety scale（SDS/SAS）. 372 questionnaires were finished by face to face. According to the Stages of Reproductive Aging Workshop +10 system, they were divided into four groups: premenopause group（n=１０５）, early transition group（n=１１０）, late transition group（n=８４）, and postmenopause group（n=７３）. Results：There were significant differences in the degrees of menopausal symptoms, SDS, SAS, Kupperman scores, and incidences of anxiety and depression among four groups（P＜0.05）. Hot flashes, sweating, heart palpitations were related to depression and anxiety, while vaginal dryness and painful intercourse were related to anxiety. Kupperman scores were correlated with SDS, SAS（r=0.465, 0.421, P＜0.001，r2=0.22，0.18）. SDS scores were positively correlated with SAS scores（r=0.801， P＜0.001，r2=0.64）. Conclusions：Menopausal symptoms, depression and anxiety can occur in women aged over 40 years, with the increasing trend following the reproductive aging. There are significant correlations between menopausal symptoms and depression and anxiety, and interaction between depression and anxiety.

Key words: Menopause, Perimenopause, Postmenopause, Depression, Anxiety