国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2021, Vol. 40 ›› Issue (6): 452-455.doi: 10.12280/gjszjk.20210341

• 论著 • 上一篇    下一篇

IVF/ICSI-ET治疗女性的社会资本和抑郁状态的研究

王丹妮(), 陈任, 徐千花, 王婕妤   

  1. 230032 合肥,安徽医科大学公共卫生学院（王丹妮）,卫生管理学院（陈任）;安徽医科大学第一附属医院妇产科生殖医学中心（徐千花,王婕妤）
  • 收稿日期:2021-07-29 出版日期:2021-11-15 发布日期:2021-11-30
  • 通讯作者: 王丹妮 E-mail:wangdanni@ahmu.edu.cn
  • 基金资助:
    国家自然科学基金青年项目(72004001);国家自然科学基金面上项目(71874002)

Analysis of Relationship between Social Position of Strong Network and Depression Status in Women Undergoing IVF/ICSI Treatment

WANG Dan-ni(), CHEN Ren, XU Qian-hua, WANG Jie-yu   

  1. School of Public Health (WANG Dan-ni), School of Health Services Management (CHEN Ren), Anhui Medical University, Hefei 230032, China; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230031, China (XU Qian-hua, WANG Jie-yu)
  • Received:2021-07-29 Published:2021-11-15 Online:2021-11-30
  • Contact: WANG Dan-ni E-mail:wangdanni@ahmu.edu.cn

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摘要：

目的: 调查体外受精/卵细胞质内单精子注射-胚胎移植（IVF/ICSI-ET）治疗女性的社会资本和抑郁状态,分析两者的关系。方法: 选择2020年12月—2021年2月于安徽医科大学第一附属医院生殖医学中心就诊行IVF/ICSI-ET治疗的104例女性患者进行问卷调查。对患者进行填答培训后,由患者自行填答。采用抑郁筛查自评量表（PHQ-9）评估抑郁,采用“位置生成法”测量社会资本。采用多元线性回归分析社会资本与抑郁状态的关系。结果: IVF/ICSI-ET治疗时间中位数为2年,治疗女性PHQ-9得分的中位数为16.00分,四分位数（P25,P75）为（15.00,18.00）分,显著抑郁检出率为52.9%（55/104）。本研究将强关系网界定为配偶与亲属,IVF/ICSI-ET治疗女性的配偶职业声望中位数为73.5分,亲属职业声望上攀值中位数为79分。多元线性回归分析显示,IVF/ICSI-ET治疗女性强关系网的社会位置与IVF/ICSI-ET治疗女性的抑郁水平升高相关（P<0.05）。结论: IVF/ICSI-ET治疗女性强关系网的社会位置高是其抑郁的危险因素。应针对性地进行心理干预,提高患者及其家庭的生育与生活的质量。

关键词: 体外受精, 胚胎移植, 精子注射,细胞质内, 社会资本, 抑郁

Abstract:

Objective: To investigate the social capital and depression status in women undergoing in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET), and to analyze their relationship. Methods: 104 female patients were selected from the Reproductive Medicine Center of the First Affiliated Hospital of Anhui Medical University, who are planned the IVF/ICSI-ET treatment from December 2020 to February 2021. After the patients were trained in answering, the patients should answer the questions by themselves. The PHQ-9 scale was used to assess depression, and the "position generation method" was used to measure the social capital of patients′ strong social network. Use multiple linear regression to analyze the relationship between the social capital and depression status. Results: The median of treatment duration was 2 years in those women undergoing IVF/ICSI-ET treatment. The median of PHQ-9 score was 16.00, P25 and P75 scores were 15.00 and 18.00, and the self-reported depression symptoms rate was 52.9% (55/104). Our study defined strong social networks as spouse and relatives. The occupational value of the spouse (Median, 73.5 points) and the occupational accessibility of relatives (Median, 79 points) were associated with the increased depression level of those women undergoing IVF/ICSI treatment. Conclusions: The high social position of the strong social network of women undergoing assisted reproductive treatment is a risk factor of depression for these women. The targeted psychological interventions should be carried out to improve the quality of both fertility and life of these women and their families.

Key words: Fertilization in vitro, Embryo transfer, Sperm injections, intracytoplasmic, Social capital, Depression