国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2013, Vol. 32 ›› Issue (2): 123-126.

• 综述 • 上一篇    下一篇

丙型肝炎病毒感染对精子和辅助生殖技术结局的作用

李 苗,朱依敏   

  1. 310006 杭州，浙江大学医学院附属妇产科医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-03-15 发布日期:2013-03-15
  • 通讯作者: 朱依敏

Effect of Hepatitis C Virus Infection on Sperm Quality and Outcome of Assisted Reproductive Technology

LI Miao，ZHU Yi-min   

  1. Women's Hospital，School of Medicine，Zhejiang University，Hangzhou 310006，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-03-15 Online:2013-03-15
  • Contact: ZHU Yi-min

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摘要： 丙型肝炎病毒（HCV）感染尤其是围生期HCV的感染近来备受关注。男性精液和精子中检出较低浓度的HCV RNA，HCV患者的精液质量包括常规和生物功能参数的下降和HCV患者男性生育功能的明显降低，证实HCV可以影响男性生殖系统并可能造成垂直传播风险。辅助生殖技术（ART）在很好地解决HCV男性患者生育的同时极大地降低了HCV围生期传播，但HCV患者子代的健康仍不容忽视。

关键词: 肝炎病毒属, 精子, 生殖技术, 辅助, 妊娠结局, 健康状况

Abstract: HCV infection attracted extensive attention, especially HCV infection in the perinatal period. HCV-RNA can be detected in semen and sperm even at low level. Patients with HCV infection had the impaired sperm parameters, including routine analysis and biofunctional parameters, which suggested that HCV infection impacted male fertility. Those HCV couples can obtain their pregnancies by assisted reproductive technology （ART）, and the risk of HCV transmission in perinatal period can be reduced, while health of their descendents can not be ignored.

Key words: Hepacivirus, Spermatozoa, Reproductive techniques, assisted, Pregnancy outcome, Health status