Abstract:

Most of vaginal cancer is transferred from other primary site, while primary vaginal cancer is rare in clinical practice. Primary vaginal cancer is often found in postmenopausal women. At present, the treatment standard of vaginal cancer has not been unified, and the individualized treatment is mainly based on the location of the lesion, tumor stage and pathological type. The radiotherapy is the main treatment. However, the radiotherapy has many long-term complications, such as vaginal sclerosis and stenosis, which seriously affect the quality of life of young patients. Due to the persistence of high-risk HPV infection, the incidence of primary vaginal cancer has increased in young women. We reported a case of young patients with primary vaginal adenocarcinoma who underwent radical surgery, vaginoplasty and postoperative adjuvant chemotherapy for 6 courses. Now, the treatment has been completed for 12 months, and there is no recurrence trace. The relevant literature was reviewed, so as to discuss the clinical diagnosis and treatment of young patients with vaginal cancer.

Key words: Vaginal neoplasms, Adenocarcinoma, Therapy, Prognosis, Laparoscopy, Gynecologic surgical procedures, Case reports