Journal of International Reproductive Health/Family Planning ›› 2024, Vol. 43 ›› Issue (1): 24-27.doi: 10.12280/gjszjk.20230208

• Case Report • Previous Articles     Next Articles

Triplet Pregnancy Complicated by Twin Reversed Arterial Perfusion Sequence after Assisted Reproductive Technology: A Case Report and Literature Review

LI Ting-ting, TAN Xiao-fang, SHI Wei-hong()   

  1. Reproductive Medicine Center, Affiliated Maternity and Child Health Care Hospital of Nantong University, Nantong 226007, Jiangsu Province, China
  • Received:2023-05-19 Published:2024-01-15 Online:2024-01-31
  • Contact: SHI Wei-hong, E-mail: swh8288@126.com

Abstract:

Twin reversed arterial perfusion sequence (TRAPS) is a rare and severe complication of monochorionic twin pregnancies, due to abnormal placental-fetal vascular anastomosis, which is characterized by absence of heart or loss of normal cardiac structure in one twin. We reported a case of triplet pregnancy complicated by TRAPS after assisted reproductive technology. Two cleavage-stage frozen embryos were transferred, one of which developed into monochorionic twin pregnology. The TRAPS was diagnosed by ultrasound at 8+5 weeks. However, due to personal factors, the patient did not intervene in a timely manner and the pump twin died. Another single fetus developed normally until full term delivery. If the treatment is needed, as for the technique of choice to interrupt the vascular supply to the acardiac twin, the radiofrequency ablation of the intrafetal vessel is usually the preferred approach. However, the best timing of intervention is still debated.

Key words: Reproductive techniques, assisted, Twins, monozygotic, Pregnancy, triplet, Twin reversed arterial perfusion sequence, Diagnosis, Therapy