Journal of International Reproductive Health/Family Planning ›› 2023, Vol. 42 ›› Issue (6): 524-528.doi: 10.12280/gjszjk.20230276

• Review • Previous Articles    

Research Progress of Atypical Polypoid Adenomyoma of the Uterus

XIAO Wan-ting, ZOU Qian()   

  1. School of Medical, Wuhan University of Science and Technology, Wuhan 430065, China (XIAO Wan-ting);Department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China (ZOU Qian)
  • Received:2023-07-06 Published:2023-11-15 Online:2023-11-09
  • Contact: ZOU Qian E-mail:13017226@qq.com

Abstract:

Atypical polypoid adenomyoma (APA) is a rare uterine epithelial and stromal tumor. The pathogenesis of APA is not clear, and it may be related to the increased level of estrogen. The main clinical manifestations were irregular vaginal bleeding and infertility. The characteristics of imaging examination of APA are atypical, the diagnosis depends on histopathology. The tissue structure under the microscopy is often complex and diverse. Immunohistochemistry is an important method to assist the diagnosis. APA is a benign tumor, but with malignant potential, there is a risk of progression into endometrial cancer. It is easy to miss diagnosis or misdiagnosis clinically. At present, the clinical treatment strategy of APA is to select the individualized treatment according to the fertility requirements, age and postoperative pathological diagnosis. The pathogenesis, clinical manifestations, diagnosis, treatment and prognosis of APA were reviewed.

Key words: Atypical polypoid adenomyoma, Clinicopathology, Immunohistochemistry, Therapy, Follow-up