Research Progress on Resveratrol in Gynecologic Malignant Tumor

doi:10.12280/gjszjk.20250260

Abstract

Abstract:

Ovarian cancer, cervical cancer and endometrial cancer are the three common malignant tumors in gynecology, and exploring safer and more efficient treatments to improve the long-term survival rate and life quality of patients has become a hot topic in the current research. Resveratrol (RES), a natural polyphenolic compound, exists in a variety of plants. In recent years, a large number of studies have shown that RES has a certain value in the treatment of malignant tumors. The mechanism of RES anti-tumor role is very complex, including anti-inflammatory, immunomodulation, inhibition of tumor proliferation and metastasis, promotion of autophagy and apoptosis, and inhibition of angiogenesis. In this paper, we review the role and mechanism of RES in the three major gynecologic malignant tumors, in order to provide a scientific basis for the development of RES clinical application in the treatment of gynecologic malignant tumors.

Key words: Resveratrol, Genital neoplasms, female, Carcinoma, Ovarian neoplasms, Uterine cervical neoplasms, Endometrial neoplasms

XIE Jiu-mei, WANG Yu, CHEN Xiang-nan, ZHANG Li-qian, WU Xiao-ke. Research Progress on Resveratrol in Gynecologic Malignant Tumor[J]. Journal of International Reproductive Health/Family Planning, 2025, 44(6): 524-528.

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