Abstract:

It is devecoping gradually for the research and application of continuous administration of
combined oral contraceptives was developed according to the demand of women which has different dosing
regimens and days of extended use. It showed some advantages of continuous administration including better
efficacy of contraception，improvement of pre-menstrual syndrome，treatment of endometriosis-related dysmenorrhea
andpelvic pain and melioration ofmood.In themeantime, ithaslessbleeding,noabnormalendometrialfindings,
low-risk thrombosis,normal parameters of thyroid hormones, androgen and hemostasis and no increasing side
effects.Furtherattention mustbe paid.

Key words: Combined oralcontraceptives, Continuous administration, Advantage, Safety