Abstract: Objective: To observe therapeutic efficacy of the oral Pudilan Xiaoyan oral liquid combined with topical iodophor external preparation in the treatment of candidal balanoposthitis. Methods：120 cases of candidal balanoposthitis were randomly divided into the treatment group and the control group. 60 cases in the treatment group were given the Pudilan Xiaoyan oral liquid combined with the topical iodophor preparation，and 60 cases in the control group were given the topical use of 2% miconazole cream. The regression times of pruritus，erythema, papule blisters, maceration and erosion after treatment in two groups were recorded. Results：After 10 days′ following-up，the total effective rate of the treatment group was 96.67% and that of the control group 86.67%. There was statistical significance in the total effective rates（P＜0.05）. The regression times of pruritus，erythema, papule, blisters, maceration and erosion in the treatment group（1.35±0.16days, 1.43±0.38days, 5.72±0.66days, 2.43±0.39days, 4.62±0.65days and 3.32±0.36days) were significantly decreased than those in the control group（2.32±0.56days, 2.63±0.60days, 8.31±1.32days, 3.93±0.81days, 7.63±1.27days and 4.62±0.55days， t values were 12.900 9, 13.087 9, 13.594 0, 12.924 3, 16.342 5 and 15.318 9, P＜0.001）. Conclusions：The Pudilan Xiaoyan oral liquid combined with the topical use of iodophor external preparation can be recommended in the treatment of candidal balanoposthitis, with the advantages of the inhibited local inflammation and the decreased regression times of pruritus，erythema, papule, blisters, maceration and erosion, and the shorten disease course.

Key words: Pudilan Xiaoyan oral liquid, Anti-inflammatory agents （ＴＣＤ）, Iodophors, Balanitis, Candidiasis, Miconazole, Ointments