Abstract: In recent years, human demand for fertility preservation has increased dramatically under the catalysis of social and personal factors such as the cancer and ovarian diseases increased year by year. More and more older single women seek "reproductive insurance". It is or will be a major challenge to meet this demand. For those older single women who demand for fertility preservation, the best way at present is to cryopreserve her oocytes at the suitable age by vitrification freezing method. However, there will be huge challenges from ethical, social and even legal controversy when the fertility preservation be used in older single women. This paper summarizes the application of egg freezing in older single women at present and the relevant ethical issues, as well as the possible solution, in order to promote the rational face of this problem.

Key words:  Fertility preservation, Fertility, Ovum, Freezing, Cryopreservation, Reproductive techniques, assisted, Older single women, Ethics, medical