Abstract: Poor ovarian response (POR) is the pathological state in which the response of ovaries to gonadotropin (Gn) stimulation is poor during the controlled superovulation (COH). With the development of society, women′s childbearing age postponed generally, and the "two-child policy" liberalized, the number of advanced women who want to have children has been increasing year by year. It is true that the incidence of POR is higher in women aged over 40 years. How to solve the fertility problem of POR patients is a hot topic in the field of assisted reproduction. Growth hormone and dehydroepiandrosterone have been tried as a pretreatment of Gn in those POR patients, which may improve the clinical outcomes of assisted reproductive technology. This article reviews the research progress of the clinical application of growth hormone and dehydroepiandrosterone in POR patients as a pretreatment of Gn.

Key words: Poor ovarian response, Growth hormone, Dehydroepiandrosterone