Journal of International Reproductive Health/Family Planning ›› 2019, Vol. 38 ›› Issue (2): 137-141.

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Sperm-Related Factors of Recurrent Spontaneous Abortion

ZHANG Xin-yue,WANG Hui,QIAN Yun   

  1. Clinical Center for Reproductive Medicine,Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,China(ZHANG Xin-yue,QIAN Yun);State Key Laboratory of Reproductive Medicine,Department of Histology and Embryology,Nanjing Medical University,Nanjing 211166,China(WANG Hui)
  • Received:2018-10-25 Revised:2018-12-16 Published:2019-03-15 Online:2019-03-15

Abstract: The main risk factors of recurrent spontancous abortion(RSA) include genetic, anatomical and endocrine factors, infection, immune dysfunction, pre-thrombotic state, systemic diseases of pregnant women and environmental factors. Clinical studies have shown that sperm quality is closely related to embryo development potential. The sperm-related factors of RSA, a variety of abnormalities in traditional semen parameters, sperm function parameters and sperm DNA / chromatin integrity, were reviewed, which provides a reference for clinical diagnosis and treatment of RSA.

Key words: Spermatozoa, Abortion, habitual, Sperm motility, DNA Fragmentation

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