Abstract: Transverse facial cleft is a congenital facial malformation that seriously affects the beauty and survival of newborns, and unilateral cleft is common. The incidence of transverse facial cleft is very low, and the etiology remains unknown. At present, there is no clear and effective means to screen the disease before or during pregnancy. However, it is very easy to diagnose according to its clinical manifestations after delivery. Surgery is main therapeutic method of transverse facial cleft to correct facial deformity, but the best surgical method is still uncertain. In this paper, a case of transverse facial cleft was reported, and the related literatures were reviewed, so as to improve our understanding of the disease.

Key words: Infant, newborn, Mouth abnormalities, Diagnosis, Therapy, Case report