Abstract: Objective：To explore the factors related to prognosis of endometrial carcinoma, so as to improve accordingly clinical treatment. Methods：All the clinical data of 225 cases of endometrial carcinoma, from January 2003 to June 2010, was analyzed. The Kaplan-Meier test and multivariate Proportional hazards regression model（Cox regression） were used for finding those risk factors related to the prognosis of endometrial carcinoma. Results：The overall 5-year survival rate was 90.6%. The Kaplan-Meier test suggested that the FIGO surgical stage, histological grade, depth of myometrial invasion, pathological type, postoperative adjuvant therapy, lymph node metastasis and peritoneal cytology be related to the survival rate（P＜0.05）. There was not significant difference in the survival rate between patients with and without the lymphatic nodes removed（P＞0.05）. Interestingly, there was not significant difference in the survival rate between those early stage patients with and without adjuvant therapy （P＞0.05）. The Cox regression showed that the pathological type, FIGO surgical stage and histological grade were the independent risk factors of the prognosis of endometrial carcinoma（P＜0.05）, and that the prognosis of those patients with the late pathological stage and poor histological grade was dissatisfactory. Conclusions：The overall 5-year survival rate of endometrial carcinoma was satisfactory. The pathological type, FIGO surgical stage and histological grade are the independent predictive factors for the prognosis of endometrial carcinoma. Meanwhile, the depth of myometrial invasion and the peritoneal cytology are not related to the prognosis of endometrial carcinoma.

Key words: Endometrial neoplasms, Prognosis, Survival rate, Proportional hazards models