Journal of International Reproductive Health/Family Planning ›› 2025, Vol. 44 ›› Issue (2): 166-170.doi: 10.12280/gjszjk.20240495

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Analysis of the Relationship between "Liver Master Sentiment" and Hyperemesis Gravidarum

GUAN Mu-xin, YANG Xin-ming, WANG Yu, LU Feng-juan, SHI Bai-chao, WEI Shi-yan, CHEN Xiang-nan, WU Xiao-ke()   

  1. Graduate School, Heilongjiang University of Chinese Medicine, Harbin 150040, China (GUAN Mu-xin, LU Feng-juan, SHI Bai-chao, WEI Shi-yan, CHEN Xiang-nan); Department of Gynecology Ⅰ, The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China (YANG Xin-ming, WANG Yu, WU Xiao-ke)
  • Received:2024-10-09 Published:2025-03-15 Online:2025-03-10
  • Contact: WU Xiao-ke, E-mail: xiaokewu2002@vip.sina.com

Abstract:

The hyperemesis gravidarum refers to the nausea and vomiting of pregnancy or the hyperemesis related to pregnancy, affecting up to 80% of pregnant women, which even lead to the abnormal fetal growth and development in severe cases. Psychological factor are an important cause, and the emotional and psychological disorder has a bidirectional effect on the pernicious vomiting. The long term of psychological and physiological stress can increase the risk of illness. Psychoanalytic theory suggests that patients with pernicious vomiting have potential mental problems, and that these mental problems can be transformed into physical symptoms. Traditional Chinese medicine believes that emotions are governed by the liver, and the physiological characteristics and functions of the liver can regulate psychological stress responses. If emotions are not smooth and liver qi is depressed, it can easily lead to the pernicious vomiting. Modern research has also confirmed that psychological factors such as depression and anxiety are related to pregnancy disorders, which may be triggered by the gastrointestinal dysfunction due to psychological and social stress. Traditional Chinese medicine treatment for the hyperemesis gravidarum includes methods such as clearing the liver and stomach, reducing nausea and vomiting, moistening the wood, promoting diuresis, regulating the liver, relieving depression, and harmonizing qi and blood. The commonly used drugs include Huanglian, Suye, Zhuru, Jiangbanxia, Chenpi, Huangqin, etc. The formula includes the modified Wendan Tang, Jupi Zhuru Tang, Guizhi Tang, etc. In Western medicine treatment, good partner support can alleviate the severity of nausea and vomiting of pregnancy. The guidelines of the Royal College of Obstetricians and Gynecologists in the UK emphasize the assessment of mental health status during pregnancy and postpartum period, advocate multidisciplinary team participation, and use the mindfulness based stress relief methods and other psychological interventions to improve patients' quality of life.

Key words: Hyperemesis gravidarum, Syndrome differentiation of emotions, Emotional regulation, Psychological factor, Based on liver therapy