Abstract: Objective: To investigate the clinical outcomes of intrauterine insemination （IUI） in infertility women with endometriosis in half year after laparoscopic treatment. Methods：Ninety-eight patients with endometriosis （stage Ⅰ-Ⅲ） treated by laparoscopy, from January 2010 to December 2012 at Zhongshan People′s Hospital, were divided into three groups: nature cycle plus IUI（NC+IUI）, controlled ovarian hyperstimulation plus IUI（ＣＯＳ＋ＩＵＩ）， and expectant treatment without IUI（ET control）, with the informed consent. The pregnancy rates of three groups in half year after operation were compared. Results：The pregnancy rate per cycle, and the cumulative pregnancy rate in half a year were 6.1%（12/197） and 28.6%（12/42） in the ET control group, 6.6%（4/61） and 10.5%（4/38） in the NC+IUI group, and 14.8%（4/27） and 22.2%（4/18） in the COS+IUI group. Interestingly, there were no significant differences in those rates among three groups（P＞0.05）. Conclusions：There is not significant difference in the pregnancy rate in those infertility patients with endometriosis （stage I-III） in half year after the laparoscopic treatment combined with IUI and without IUI （expectant treatment）. Of course, it is necessary to study further with more samples.

Key words: Insemination, artificial, homologous, Endometriosis, Reproductive techniques, assisted, Laparoscopes, Infertility, female